Yes, it's in shot form, you give yourself the shot weekly. I've been on them for over two years now. I take a VERY high dose of MTX because I have LGL Leukemia, as well as lupus. MTX is also used to help keep this type of leukemia stable but at much higher doses than for lupus.
I when I was on the lower doses for my lupus I rarely had side effects. Now that I'm on such a high dose, my fair is falling out, I've got terrible sores in my mouth, and I'm on anti nausea medication at least twice a day.
The medication, at least for me, comes in a vial. I have to draw it up into a syringe and change needles and then give myself the shot in thigh. I do this weekly, if I can answer any other questions, please feel free to ask.
DX- RA, Lupus, Fibro, LGL Leukemia, Obstructive & Central Sleep Apnea, Pulmonary Hypertension, Bells Palsy, Gastroparsis, Blood Clots, Glaucoma, Chronic Pericarditis & Pleurisy, Severe Anemia. Way to many medications to list.