Sorry to hear that your Dr's called things the wrong way with the brain lesions. I know that we've had several folks over the years I've been a member on the forum who had lesions and there was a debate over Lupus vs MS.
I can think of one member currently who may be able to answer your question, hopefully, she'll see this thread and respond. I've never had any lesions in my brain. Most of my organ involvement is in my heart, lungs, GI tract, skin, and joints.
My anemia is really bad due mostly from my leukemia, but my lupus adds to the condition too. So, I've got tons of others blood flowing thru my veins like you. I average 2 to 6 units every 45 days or so.
I hope that you continue to do well on the plaquenil and I hope that they figure things out totally for sure really soon. Welcome to the forum, feel free to ask any questions you can think of.
DX- RA, Lupus, Fibro, LGL Leukemia, Obstructive & Central Sleep Apnea, Pulmonary Hypertension, Bells Palsy, Gastroparsis, Blood Clots, Glaucoma, Chronic Pericarditis & Pleurisy, Severe Anemia. Way to many medications to list.