Autoimmune diseases do run in families. Not necessarily the same diseases but genes are a factor and you can inherit genes that make your immune system susceptible to a disruption. Depending on what you are exposed to determines what you get.
Keep in mind that ana is present in many diseases and can be present even when there is no disease.
MCTD (SLE Lupus, polymyositis, scleroderma). Diagnosed 2005. Kidney, liver, GI tract, dysphagia, raynauds, barretts esophagus, quadriplegic in 2005. Recovered and now active in downhill skiing, golf, hiking. Meds: amlodipine, benezapril, omeprazole, potassium, folic acid, vitamins, maxide.
Remain Optimistic and you can overcome.