Treatment of lupus is long term, usually in years. Same for using HCTZ. Both have side effects, particularly prednisone and most docs will put their patient on some other drug that is better tolerated long term and slowly, slowly taper pred.
I was on pred for 6 years and also Imuran. Been off both for more than 3 years but lupus is acting up again and I might have to start them again...hope not. I take HCTZ and lisinopril for my kidneys but will be on those forever.
MCTD (SLE Lupus, polymyositis, scleroderma). Diagnosed 2005. Kidney, liver, GI tract, dysphagia, raynauds, barretts esophagus, quadriplegic in 2005. Recovered and now active in downhill skiing, golf, hiking. Meds: amlodipine, benezapril, omeprazole, potassium, folic acid, vitamins, maxide.
Remain Optimistic and you can overcome.