Sounds like you need to see another doctor who knows how to treat autoimmune diseases. Since you have other issues it might take more than one doctor to address your problems. Plaq is an "entry level" drug and is used primarily to treat mild cases of lupus and other diseases. For more serious cases or if it doesn't work other meds are usually tried. Prednisone works in most cases and quickly but is not a good drug to take long term so others are introduced and prednisone usually tapered. There are many different treatment options to try.
As I am sure you realize, you only have so much energy and need to simplify your life as best you can. If you get effective treatment you could feel much better in time and be able to handle things.
MCTD (SLE Lupus, polymyositis, scleroderma). Diagnosed 2005. Kidney, liver, GI tract, dysphagia, raynauds, barretts esophagus, quadriplegic in 2005. Recovered and now active in downhill skiing, golf, hiking. Meds: amlodipine, benezapril, omeprazole, potassium, folic acid, vitamins, maxide.
Remain Optimistic and you can overcome.