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New Member

Date Joined Jun 2015
Total Posts : 2
   Posted 6/20/2015 2:01 AM (GMT -6)   
Hello, I was diagnosed with Lupus about 5 months ago. My doctor had me take ibuprofen and Plaquenil. However once I went back to the doctor three months later, they ran blood test and my liver functioning test came back with high numbers. I was then sent to a liver specialists who ran more test and advised me to stop taking the ibuprofen, the test came back normal except the liver functioning. A week later I went back and my number came down slightly, I was then encourage to stay off the ibuprofen and come in to be tested weekly the third week and the number fell back to what they were the first time they were elevated. However, I learned that plaquenil also affects your liver so I have now taken it upon myself to stop the plaquenil. I am having a constant pain in the area where the liver is located. Anyhow, I am wondering if maybe prenzone might be a better fit for me? Has anyone else had liver issues with plaquenil?

Regular Member

Date Joined May 2014
Total Posts : 68
   Posted 6/20/2015 10:00 AM (GMT -6)   
Have you or any of your dr's considered that lupus is affecting your liver? I wouldn't stop the plaquenil without talking to your rheumy. You might even want to see a liver specialist who has experience with autoimmune diseases affecting the liver.
Diagnosed with SLE lupus October 2014.

Veteran Member

Date Joined May 2005
Total Posts : 7723
   Posted 6/20/2015 9:35 PM (GMT -6)   
Don't stop your medication without consulting with your Dr. The medication may be HELPING your liver!!!!

Are you seeing a rheumatologist? Plaquenil and Prednisone are used for very different reasons, only your Dr knows all your symptoms and medications to be able to suggest a medication.
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2002
"Life is far too important to be taken seriously." - Oscar Wilde
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