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New Member

Date Joined Oct 2014
Total Posts : 6
   Posted 9/7/2015 10:41 AM (GMT -6)   
I am diagnosed as lupus a year ago and was started with azathioprine, prednisolone and hydroxychloroquine since then. i took azathioprine for around 6 months and found to have low wbc count in my doctor's visit. So on doctor's advice azathioprine was withheld. Its been almost 3 and half months my wbc count ranges from 3000 to 4000(lower side) despite of quitting azathioprine. Has anyone gone through this phase? pls share if any.

Veteran Member

Date Joined May 2005
Total Posts : 7723
   Posted 9/8/2015 7:41 PM (GMT -6)   
Auto-immune disorders such as Lupus can often cause low WBC's. It sounds as thought the Imuran (azathioprine) is not necessarily helping you with this part of your disease.

Other similar medications that may be of help are Cellcept and MTX. These, along with Imuran, are the 3 medications most often used (after Plaquenil and Prednisone) to control Lupus. I wouldn't be surprised if your Dr doesn't try one of these soon - or maybe you can ask about them. It isn't known who or why one person is helped by one of these 3 and another is not -- we have to keep trying until the medication is properly matched to the patient.

Best wishes,
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2002
"Life is far too important to be taken seriously." - Oscar Wilde

Veteran Member

Date Joined Jan 2007
Total Posts : 610
   Posted Yesterday 7:19 AM (GMT -6)   
I am allergic to azathioprine, and I was hospitalized due to pancytopenia. The specialist withheld the med. I am now on cellcept and it's a magic for me.
DX SLE 1988; APS (Antiphospholipid Syndrome); High-Blood Pressure; levothyrodicine 75 mg; Cellcept 1500 mg; Warfarin; Calcium, Folic Acid 5 mg; Simvastin; Candesartan 4 mg; multi-vitamin
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