There are many website which will check drug interactions for you. My personal favorite is /www.drugs.com/drug_interactions.html
. I don't see any interactions between Plaquenil and Prazosin.
Are you being treated by a rheumatologist? If you've been given a "probable" Lupus diagnosis, that is the specialist you need to see. There are many treatments beyond Plaquenil that the rheumy will know about
but a PCP may not.
Plaquenil does take a while to kick in, but usually it's said to be 2-3 months rather than 6.
I hope you feel better soon!
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2000DIAGNOSING LUPUS & HW's LUPUS 101
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