It's very common to have stomach issues that settle down in 5-10 days, especially on the generics - most people do better on the name brand, Plaquenil. If it lasts more than 10 days contact your Dr & try the name brand if you can.
You can try something over-the-counter to address the stomach issues, or your Dr may recommend something.
Plaquenil may interact with acetaminophen, cancer medications, tuberculosis medications, birth control pills or hormone replacement therapy, arthritis medications, ACE inhibitors, antibiotics, antifungals, cholesterol medications, HIV/AIDS medications, NSAIDs (non-steroidal anti-inflammatory drugs), or seizure medications. So if you are taking any other these it may be contributing to stomach upset.
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2000DIAGNOSING LUPUS & HW's LUPUS 101
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