Help two high Ana titers

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New Member

Date Joined Feb 2017
Total Posts : 2
   Posted 2/15/2017 4:26 PM (GMT -6)   
Two years ago I had a high Ana titer of 1:640 homogeneous with s rash on all my joints and stomach/ bowel pains. Went to the rheumatologist and everything negative. Had the rash for 7 months. Doctors did think to have skin biopsy done.

Two weeks ago my Ana titer came back 1:1280 speckled. The past 6 weeks had sudden onset on joint pain in my knees, ankles, hip, shoulders and neck. After my Ana came back high then a couple red disc shaped spots appeared on my hip, my mouth erupted in sores/ ulcers, tongue swollen, no the inside of my lips are swollen. Bad fatigue and exhaustion. The dermatologist couldn't do a biopsy because the spots had started to clear up after taking anti inflammatorys.

I have a family history of lupus (2 aunts), raynauds, tremors, spider veins and rheumatoid arthritis. I have confirmed raynauds, essential tremors in my hands and spider vines.

My main question is it possible two have two high Ana's and not have any auto immune disease? I'm waiting on the results of my more detailed blood work and my rheumatologist appointment is not until March 24th.

Post Edited (Redheavens) : 2/15/2017 2:29:17 PM (GMT-7)

Veteran Member

Date Joined May 2005
Total Posts : 7723
   Posted 2/15/2017 5:55 PM (GMT -6)   
A positive ANA does not necessarily mean you have an autoimmune disease. However, with your other symptoms you certainly seem to have something going on!

"A positive antinuclear antibody (ANA) test does not automatically mean you have lupus.

Your immune system is your body's natural defense against disease. A positive ANA blood test shows that your immune system is making an antibody (protein) that reacts with components of your body's cells. This is called autoimmunity and may or may not be harmful to your body.

So while a positive ANA may be associated with an autoimmune illness like lupus, it does not mean you have the disease. Approximately 20% of the normal population will have a positive ANA test; positive tests are also seen in other conditions, such as thyroid disease, certain liver conditions, and other autoimmune diseases."

Here is more information: /
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2000
"Life is far too important to be taken seriously." - Oscar Wilde

New Member

Date Joined Feb 2017
Total Posts : 2
   Posted 2/15/2017 6:47 PM (GMT -6)   
I do agree.. it's just the reading I've done said normal healthy people will test positive for Ana but it's normally in low range of 1:40 to 1:160. That 1:320 is considered the cusp and 1:640, 1:1280 and higher is considered very concerning. It's not a good format when you check your test results on the portal for the drs office and start googling before even hearing from your dr. Lol
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