I have been having symptoms for the past few years. It started out with horrible breast pain. Then one armpit started hurting and burning..it moved to the other armpit eventually. I had a mammogram and everything was fine. Then the base of my skull on each side started hurting for 3 months. I had a cervical MRI and it was fine. Then one day my jaw line and throat started to be tender. All of these things I believe are glands and nodes. These symptoms happen frequently. I have been getting the malar rash off and on. Today, I mowed, then showered and I had the butterfly rash. My face feels tight. I've been on antibiotics a few times over the past few years and it helps but comes right back. I have taken prednisone probably 4 or 5 times over the last few years and it helps my symptoms but as soon as I've finished the prescription, symptoms come back. In between all of this I got a few boils in my armpit and was on antibiotics for 20 days and developed a rash. I'm not ure if it was due to the antibiotics or not. I went to the care because the rash wasn't going away. The nurse practitioner said it looked like vasculitis or petechiae so they did a CBC, which apparently was normal because they just said I developed a rash and put me on prednisone. It went away. I don't really have joint pain. I do have Raynauds. My fingers turn white when I'm cold or nervous. I do have some muscular pain. I've started to get spider veins all over my les. I have a blue line under my eye. I have upper cheek edema. I've seen several doctors. My most recent did do a ANA and it was negative. So, that was it. I've had gland tenderness for close to years..So, my question is, could I still have lupus or an autoimmune disease with a negative ANA? I'm sorry for the rambling, but I'm just not sure what to do anymore. Any advice??? Anybody? Please!