If you read our thread, Lupus 101, it contains some tips on avoiding flares. Deep restorative sleep, healthy eating, mild regular exercise, avoiding the sun, minimizing stress (of all kinds, mental, emotional, physical stress) - all of these help.
After Plaquenil (the anti-malarial) the next drugs generally tried are Imuran, Cellcept, and MTX - your Dr will pick one of these 3 and try you on it for 3-5 months - if no improvement, they will try another one of these three.
I'm not sure how any of these are for rheumatoid arthritis -- we also have a forum on RA, this would probably be a good question to post over there.
Hope that helps a bit,
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2000DIAGNOSING LUPUS & HW's LUPUS 101
"Life is far too important to be taken seriously." - Oscar Wilde