Is it Lupus or Sjogren's?

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New Member

Date Joined Sep 2017
Total Posts : 4
   Posted 9/7/2017 10:12 PM (GMT -6)   
I have been feeling pretty sick for a while and seeing a whole bunch of doctors! I have quite a few symptoms that I'm not gong to go over now. I feel that I could have lupus. I saw a Rheumatologist who agreed that I likely have an autoimmune disorder. He ordered Lupus and Sjogrens tests. He told me he thinks I could have fibromyalgia and Sjodrens together, (not lupus). I got some labwork back but do not go back to discuss diagnosis for two more weeks. Its driving me crazy! I was wondering if anyone had any experience with this? I am going to post my lab results - does this look more like Lupus or Sjogrens?


-White Blood Cell- LOW- 3.8 * 1000 mm/3 (normal begins at 4.5 *1000)

-ANA Ab: Positive 1:80

-ANA IFA: Positive 1:320 (Speckled Pattern)

-SSA (Related to Sjogren's?): Moderately High and Positive

-ENA (Smith Ab + RNP): Positive

-Neut Percent: Slightly Low

-Neutro Auto Abs: Slightly Low


-Rest of Complete blood count: Normal

-C3 & C4: Normal

-CK (creatine kinase): Normal

-SSB (Related to Sjogren;s?): Normal and Negative

-double strand DNA: Normal

There is so much overlap between the two that I cannot figure it out, which in turn is driving me crazy! I've been feeling so fatigued and sick. Also, I meet 3 of the 6 criteria of sjogrens and 7 of the 11 criteria for Lupus. Please let me know if any of you have had similar results and what your final diagnosis was!

Thanks a bunch!

Carly confused confused confused confused

Veteran Member

Date Joined Mar 2007
Total Posts : 1654
   Posted 9/7/2017 11:38 PM (GMT -6)   
With positive anti Smith antibodies and your other results, it's likely SLE. Or it could be an overlap condition of SLE/Sjogren's.

Forum Moderator

Date Joined May 2005
Total Posts : 7671
   Posted 9/8/2017 6:59 AM (GMT -6)   
Neither Lupus (SLE) nor Sjogren's are diagnosed by blood tests alone, but by having significant (to the rheumy) symptoms relevant to the disease.

One of the ways they can differentiate between Lupus and Fibro is that Lupus symptoms diminish with Prednisone, while Prednisone will have no effect on Fibro symptoms.

With only 2 weeks until your appointment, try to let it go and let the Dr figure it out - they are the professionals with the education and the experience for that, you & I would only be guessing.

Concentrate on getting deep restorative sleep, eating healthy (avoiding sugars), getting mild regular exercise (walking 10 minutes counts!), and doing enjoyable things to distract you from worry!

Best wishes,
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2000
"Life is far too important to be taken seriously." - Oscar Wilde
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