ANA 1:80, minor joint pain, Hives and mucle aches

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New Member

Date Joined Dec 2017
Total Posts : 4
   Posted 1/10/2018 2:24 PM (GMT -6)   
Newish member here. Had some labs done as part of a physical with my GP. All was good and in range except for my Cholesterol ( working on that ) but my ANA was 1:80.

I have Ulcerative Colitis which in itself is considered a Autoimmune Disease. My GP wants me to go get checked by a Rhuemy because of my slightly elevated titer and some symptoms. That could point to Lupus.

I have had signs of UC for a good while. I started noticing the mucus stools and slight bleeding probably in 2014 but never went to get checked. I started having muscle and joint pain in about 2016 and I was officially diagnosed in May of 2017 after I was bleeding profusely and was swollen back there.

After getting diagnosed in about Sept of 2017 I started having random flare ups of Hives. First breakout was on my face, neck and chest. Took a Benadryl and a warm shower, it was gone 3 hours later.

After that still get random Hives on back of my legs, arms, face at times if too hot or too cold. I also get itchy armpits and hives form there too. Along with muscle slight pain mostly concentrated on one particular spot on my left bicep but happens on my right as well at times. Will at times get pain on the left side of my neck also. Ohh and also my hands fall asleep at my pinky and ring fingers. Ulnar nerve entrapment?

I was extremely stressed after being diagnosed so maybe this is all stress related but hopefully the Rhuemy can give me some answers. Anyone else in my same situation?

Post Edited (jaxzin) : 1/10/2018 12:30:50 PM (GMT-7)

Veteran Member

Date Joined May 2005
Total Posts : 7723
   Posted 1/10/2018 3:28 PM (GMT -6)   
jaxzin said...
My GP wants me to go get checked by a Rhuemy because of my slightly elevated titer and some symptoms. That could point to Lupus.

A slightly elevated ANA really is NOT diagnostically significant in the absence of other symptoms. Here is what Johns Hopkins (Maryland, USA) has to say about a positive ANA.

"A positive ANA result means that you have a higher than normal concentration of these antibodies. This is one of the tools in diagnosing lupus as well as several other autoimmune diseases, so a positive result may be related to lupus or to another disease. Or you may simply have a higher than normal concentration of these auto-antibodies that may not have any impact on your health. Even among people with lupus, ANA results can vary widely; one person can be in remission at a certain titer of ANA while another can be extremely ill at the same titer. Autoimmune diseases often have a systemic effect on the body and are very complex by nature. Your healthcare provider will interpret what the test results mean for you and may need to compare your test results as well as the severity of your symptoms over a period of time in order to make a definitive diagnosis."

Typically, four or more of the following eleven criteria must be present to make a diagnosis of systemic lupus.

1. Malar rash: butterfly-shaped rash across cheeks and nose
2. Discoid (skin) rash: raised red patches
3. Photosensitivity: skin rash as result of unusual reaction to sunlight
4. Mouth or nose ulcers: usually painless
5. Arthritis (nonerosive) in two or more joints, along with tenderness, swelling, or effusion. With nonerosive arthritis, the bones around joints don’t get destroyed.
6. Cardio-pulmonary involvement: inflammation of the lining around the heart (pericarditis) and/or lungs (pleuritis)
7. Neurologic disorder: seizures and/or psychosis
8. Renal (kidney) disorder: excessive protein in the urine, or cellular casts in the urine
9. Hematologic (blood) disorder: hemolytic anemia, low white blood cell count, or low platelet count
10. Immunologic disorder: antibodies to double stranded DNA, antibodies to Sm, or antibodies to cardiolipin
11. Antinuclear antibodies (ANA): a positive test in the absence of drugs known to induce it.

It doesn't sound to me like you really have much to worry about, but I would suggest you follow your GP's advice and have it checked out more thoroughly by a rheumatologist.

Meanwhile, is someone treating your UC? I'm not that familiar with it, but I think the symptoms you mention may be associated with your UC.

Best wishes,
Lynnwood, Lupus & Sjogren's Moderator, Dx: 2000
"Life is far too important to be taken seriously." - Oscar Wilde

New Member

Date Joined Dec 2017
Total Posts : 4
   Posted 1/10/2018 4:22 PM (GMT -6)   
Thanks for the info. I for sure am going to get checked out by the rheumy. I will post my progress here as to possibly help others. 2 more weeks until my appointment.
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