ANA results are reported as a titer. Titers are expressed as ratios, which are obtained by diluting a portion of the blood sample with saline (salt water). For example, a titer result 1:320 means that one part blood sample was mixed with 320 parts of saline and this was lowest ratio at which ANA was still detected. The lower the dilution ratio at which ANA is still detected, the higher the titer and the greater the amount of auto-antibody present.
Any amount is a positive ANA. 1:40 is a low positive, while 1:1280 is a high positive.
A positive ANA test result means that auto-antibodies are present. In a person with signs and symptoms, this suggests the presence of an autoimmune disease, but further evaluation is required to assist in making a final diagnosis. Again, some people without disease can have a positive ANA test.
Lynnwood, Dx: 2000, Found HW 2005, HW Lupus/Sjogren's Moderator May 2006-May 2018
DIAGNOSING LUPUS & HW's LUPUS 101
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