I am new to this forum and adding to this thread late, but I have a deep interest in the subject.
I got drug-induced lupus (DIL) from Remicade. This was confirmed by high ds-DNA antibodies, high anti-histone antibodies, high anti-Remicade antibodies, and various symptoms including joint pain, weakness, bouts of fatigue, occasional brief flushing on my face and chest (though I've stayed out of the sun), etc.
I too was told that the DIL should subside shortly after stopping the offending medication. We stopped the medication 12 months ago, and I am still waiting for the lupus symptoms and abnormal anti-histone antibodies to clear up. I tried taking Plaquenil twice, but both attempts caused severe diarrhea. Since I was on Remicade for Ulcerative Colitis, medicines that cause severe diarrhea are to be avoided.
Has anyone else had DIL last this long? I was on the Remicade for over 2 years before this was discovered, and I wonder if that's why my DIL is lasting longer.
My Rheumatologist has repeated tests to rule out real lupus (SLE), so we're fairly certain we're dealing with DIL here, perhaps mixed with symptoms of having an auto-immune disease: UC.