I think a few words you wrote initially count for a lot "waking up from a coma". Maybe your friend, after being unwell for so long and then finally getting the correct treatment and help is now living her life to the fullest in the way that she personally feels is right for her.
That kind of life it isn't right for you and for us here reading about it. Thing is though, drinking hard and smoking - who knows what really - can and do have a huge impact of our brains.
The feeling that she only ever did what she was "supposed" to do by others e.g. go to church, stay at home, be a mum and all of those thing meant maybe to her that she wasn't being her true self. Not saying being the way she is now being her true self, but she is totally rebelling isn't she ?
We all know that sometimes we can feel so alone. Not only with an illness of any type, but that we are taken for granted in our lives. We get on with things the same way every day and then - snap !! We kick up a bit of a fuss and we feel better. Things might change for a little time but then normally go back into the same routine.
By getting totally away from all of it, your friend seems to be shutting out the chance that she will be forced back into the life she so desperately wanted to change. What is expected of us and what we really want to do are so very diferent. We all need to be heard.
I do so hope that things improve for her and that you or indeed her husband can sit her down and have a long and meaningful talk with her. Just face to face, not involving other people, just to listen to her and actually "hear" what she is saying.