Posted 7/23/2007 11:22 AM (GMT -6)
Could you describe "focal proliferative mesangiopathic glomerulonephritis" in English?

I have no idea what that is and unfortunately a web search doesn't clear it up much. Maybe something that targets the joints?

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Posted 7/23/2007 10:32 PM (GMT -6)


         Focal proliferative mesangiopathic glomerulonephritis is a form of lupus nephritis.  It is characterized by large amounts of protein passing through the glomeruli (tiny filters) which damages the glomeruli and becomes a vicious cycle.  It doesn't "target" the joints;  however,  chronic kidney disease can cause calcium imbalances and coupled with the fact that the first line treatment is steroids;  it can wreak havoc on the bones.  I know when I first went into kidney failure I was given 1000mg of solumedrol i.v for 5 days followed by 120mg of prednisone by mouth for many weeks.  It was rough!  It took me 13 months to come off the steroids that first time.  If you do a search on mesangiopathic glomerulonephritis and the nephrotic syndrone you'll get a better picture.  My last biopsy showed a progression to global glomerulosclerosis. 

Gypsy...i'm baffled by the number of joint replacements you've  had.  Are you having infections that are causing the joints to have to be replaced?  I know the prednisone impairs your ability to heal and suppresses your immune system.  I'm sorry you've had such an ordeal.  God Bless,


Posted 7/23/2007 10:59 PM (GMT -6)
Welcome again Gypsy. I've learned something in this thread because I didn't know what folcal proliferative mesa...glomer...was either. Judy's right. You've really been through an ordeal and I just hope you can find comfort here among friends.


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Posted 7/24/2007 12:15 PM (GMT -6)
Thanks for the more user-friendly explanation...
Posted 7/24/2007 1:15 PM (GMT -6)
Just wanted to say hi gypsy and welcome to the forum. Bless your heart it sounds like you have been thru so much. I hope yo can find some answers here. I'm sure you will get as much support at you could ever need from all the great people here.

Again welcome. looking forward to getting to know you better
God Bless
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