Yes, I'm still taking the MTX. I was on Remicade for over a year and worked really well for me. My Rheumy pulled me off mainly because my ANA was rising. It's come back down since I stopped taking it. I was also getting chronic UTIs(kidney infections and stones too) and swollen glands. So even though it was working, we decided to stop it to see exactly what was going on.....both problems stopped when Remicade was discontinued. It could be Remicade specifically or it could just be a result of biologics in general. Remicade was my first biologic, so we will see what happens on the Orencia.
I think that is common for the biologics to work for only so long. Arava/MTX should help extend the time, in theory anyway. I do know a lady that has been on Remicade for almost 10 years for RA and it still works for her. So there is hope that you might find something that works for the long haul.
I was on Prednisone for a year and I know exactly what you mean. I hated it and withdrawal was pure evil. I feel for you.
It works for the most part. I still will go through cycles (usually during a flare) of not being able to sleep, but it is much better than not taking anything. It took a while for my Rheumy to convince me to try it. I was probably at the point you were and finally agreed to try something. I would like to stop taking it, but I go right back to only sleeping a few hours and it's not even good sleep. I'm learning to accept it. :)
How did you end up with both the RA/Lupus diagnosis? I ask because my diagnosis isn't clear, but we are going with RA. I'm beginning to wonder if we aren't dealing with both. My ANA usually runs 1:160 (speckled), CRP & SED rate are high, Scl-70 positive (but no skin signs of scleroderma) and everything else is normal even the Rh factor and CCP.
SLE diagnosis 10/05 now changed to RA 3/06, Endometriosis 5/05, PCOS 1990
Meds: Metformin ER 1500mg (PCOS); Loestrin BCPs (Endo); Methotrexate 15mg (RA); Metanx 5mg (RA); Orencia 750mgs (RA); Lunesta 2mg (as needed); Prevacid