Have you seen a nephrologist? Blood and protein in your urine indicates some kind of kidney involvement and should be examined. It could be lupus and given your family history it is possible but it could also be something else. Proteinuria is common in lupus patients and that is what is causing your kidney dysfunction. Do you also have edema in your feet/ankles/legs?
For most proteinuria is easily treatable with ace inhibitors. I have it and it has been completely under control for 2 years.
I would also get a second opinion from an experienced rheumatologist.
Mixed connective tissue disease (systemic lupus, scleroderma, polymyositis), Raynauds phenomena, Hypertension, Barrett's esophagus.
Meds: prednisone (6mg & tapering), 75mg imuran, lisinopril 40mg, maxide 37.5/25mg, norvasc 5 mg, folic acid, potassium, aciphex 20mg, multi vitamins.
Maintain your optimism and you can beat the odds.
"Although the world is full of suffering, it is also full of the overcoming of it." Helen Keller