You have good questions about this. I think our ANA is very misunderstood. I'm not a pro at this thing either. I wish we understood more about what it means to us....
From what I understand, our ANA is an indicator that we have the antibodies in our system. The higher the number, the more we have. It doesn't necessarily mean that with a very high number, like yours, that it means your lupus is more active. It just tells us that there are a lot of those antibodies floating around. The bigger indicator of our disease activity is the amount of inflammation that is attacking our organs, tissues etc. Someone with a lower ANA, like me (1:640) when I was diagnosed, had incredible amounts of inflammation going on. It was insane. My antibodies were fewer in number, but much more active in producing inflammation.
Does that make sense? I hope so! I'm reading this over again and wondering..... LOL. That is what I understand it to be. I hope there are others out there who can shed some more light too!
I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13
33 years old. Diagnosed with lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, seizure disorder-(miraclulously disappeared!), Libman Sach's Endocarditis, vasculitis, sacroiliitis, neutropenia, thrombocytopenia. Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, monopril, calcium, Cykolokapron, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus