J. Clark Nicholson,
I think what you're describing is caused by endorphin release from the laughter. Perhaps those of us with Lyme are more sensitive to the effects of this natural and normal release of endorphins from laughter (also released during exercise - e.g., "runner's high")...
BTW, I read your story - you are a great storyteller, I think you should write a book about your Lyme journey.
Chronic Lyme Disease, Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, Anemia, Lymphopenia, intermittant Pancytopenia, chronic malabsorption/malnutrition, etc.; G-J Tube; Currently TPN-dependent.
Meds: Zofran, Pulmicort, Vitamin B12 Shots, Heparin (to flush PICC line).