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Need information on IGM bands-help!

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Lyme Disease
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king1234
Regular Member
Joined : Nov 2006
Posts : 491
Posted 11/16/2008 11:15 AM (GMT -8)
Hi guys. I go to my LLMD tomorrow. I know she is specialized in lyme, but I want to bring supporting documents on why I think I need meds. Not only do my symptoms not match ONE disease as of now, all of my tests, scans, labs come back clear, drs are all puzzled BUT I did test pos on IGM 31 and IND on 34/41.

Some posters have said 31 is specific to lyme. Does anyone here know where I can find this info on the internet so I can print and bring with me? These drs are expensive so I dont want to risk not bringing these type of docs

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Dowa
Veteran Member
Joined : Sep 2008
Posts : 1120
Posted 11/16/2008 12:43 PM (GMT -8)
I was told it was 41 that was important for diagnosis by Dr. C's office in MN who supposedly is a specialist in Lyme.

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dorit
Regular Member
Joined : Nov 2008
Posts : 375
Posted 11/16/2008 1:13 PM (GMT -8)
hi king 1234

I dont know if I understand your question right ( I`m in europe),
you are asking for internet info refering to bands in igm / igg westernblod saying your test is positive for lyme...?!

I found this webside within my own research for information:

http://www.lymenet.de/labtests/brenner.htm ..... for the states

and maybe this one but ONLY for europe (if you have been here, and had contact with a tick)
http://www.allgaeulab.de/labor/pdf/Lyme%20Borreliose%20Labordiagnostik.pd

may be this helps you ...in case I understood your question right...

best wishes for you!!!

dorit
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JELAINEP
Veteran Member
Joined : Sep 2007
Posts : 2017
Posted 11/16/2008 1:23 PM (GMT -8)
You can get more info from the "Newbie" thread at the top of the Lyme site:

Ticker's words of wisdom about how to read your Western Blot results:

The IgM tests for a more recent infection and the IgG a longer standing one. Below is the breakdown of the Western Blot bands:

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

Band 41 is often the first to show. Bands 30, 31, 34, and 39 are all Lyme specific bands.
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king1234
Regular Member
Joined : Nov 2006
Posts : 491
Posted 11/16/2008 3:46 PM (GMT -8)

So would you think with my symptoms and a pos 31 and IND 34 41 on the IGM I do in fact have lyme? I know you are not drs, just looking for your opinion.

As I type my right pointer knuckle is getting a deep searing pain and I twitching all over.:(

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JELAINEP
Veteran Member
Joined : Sep 2007
Posts : 2017
Posted 11/16/2008 8:36 PM (GMT -8)

king1234 said...

So would you think with my symptoms and a pos 31 and IND 34 41 on the IGM I do in fact have lyme? I know you are not drs, just looking for your opinion.

As I type my right pointer knuckle is getting a deep searing pain and I twitching all over.:(

I would say "yes".  On my first LD test, EIA was positive, Western Blot negative.  Then IGM positive, then IGG and IGM positive which = NY State and CDC positive.  I continue to test postive on the IGM.


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Razzle
Veteran Member
Joined : Aug 2007
Posts : 4415
Posted 11/17/2008 2:12 PM (GMT -8)
http://www.personalconsult.com/articles/drjonesapproach.html

Dr. Jones says (in the above link) it only takes one positive Lyme-specific band to confirm exposure to Lyme.

I hope this helps - take care,
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