norepinephrine sensitivity

I don't know about sensitivity to NE, but I have had experience with Effexor. When you go off of Effexor, do it very slowly, do not stop all at once. I had severe reactions with Effexor... I took it daily around 8am and would cycle through it so quickly that I would "crash" around 5pm every day. I would wind up in a ball crying and sobbing.... and this was when everyone was saying "it's all in your head".... HUH? And when I went off of it... no one told me about the withdrawal... jeese, I LOST IT for about 3 days straight before one of my doctors said "it's the Effexor, take an Effexor". It took me a good month to "wean" myself off of it.

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Gracie: Have you ever done the Genomic Detox Profile by Great Smokie Lab, it can tell you if you are unable to detox your norepenephrine. That may be  adding to your problem. You said you have a "sensitivity" to NE and it could be that your body cannot detox it properly. Its a great test to have done and explain alot.  D

My neuro-transmitters are not normal, cant say that is from the lyme for sure. I am low in epinephine, high in norepinephine and very low in seratonin. The genomix test is VERY interesting, it also lists all drugs that your body cannot detox and that is GREAT information to have with Lyme (and other conditions as well). D

judy, high normetanephrine levels are used to diagnose a pheochromocytoma - have you and your doctor ruled that out??? it is a tumor on the adrenal gland that secretes its own norepinephrine.
i was originally diagnosed with an autonomic nervous system dysfunction (POTS), and i know that many sufferers had high Norepinephrine and normetanephrine levels. it seems pretty common in adrenal disorders that one might see high levels.
it is really unusual for one to see low levels.