ID doctors who follow the CDC guidelines a little too closely seem to want a positive test in order to diagnose Lyme. Lyme-Literate MD's tend to follow clinical signs & symptoms more than test results when diagnosing Lyme, but the diagnosis is supported when there are positive bands on a Lyme test (even if the overall test results are negative by lab or CDC standards). Part of it also depends on patient history (known tick exposure and/or history of EM rash, etc.) and which specific bands show IND or positive on the Lyme tests.
For those who were on Abx at time of exposure, perhaps IgeneX's antigen capture test would be useful. This test requires a short course of abx, followed by a urine sample collection. The theory is that the abx kill of some of the spirochetes, causing Lyme DNA to be excreted in urine, which then can be detected by the test.
Just my $.02...
Chronic Lyme Disease, Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, Anemia, Lymphopenia, intermittant Pancytopenia, chronic malabsorption/malnutrition, etc.; G-J Tube; Currently TPN-dependent.
Meds: Zofran, Pulmicort, Vitamin B12 Shots, Heparin (to flush PICC line).