minocycline and amoxicillin?

marylandgirl

Regular Member

Joined : Oct 2008

Posts : 26

Posted 12/26/2008 2:12 PM (GMT -7)

I just filled my first prescription for 100mg of minocycline and 500mg of amoxicillin today and on both prescription info it says not to take together. Should I be worried? My doctor's office is closed so I can't check with them and I would like to start taking the meds this weekend. Has anyone taken them together? Thanks for any input.

kitty9309

Regular Member

Joined : Oct 2008

Posts : 163

Posted 12/26/2008 7:41 PM (GMT -7)

Hi. I found this for you on drugs.com (drug interaction checker):

GENERALLY AVOID: Tetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by penicillins. Antagonism is more likely when low doses of either agent are administered. Therapeutic failure may result.

MANAGEMENT: This combination should be avoided if possible.

jasrich

Regular Member

Joined : Dec 2008

Posts : 29

Posted 12/29/2008 11:34 AM (GMT -7)

My LLMD has RX'ed Minocin, 100mg BID on MWF, Zithromax, 500mg QD on Sat. and Sunday and weekly IM of penicillin BA. Does the fact that I'm to have the penicillin injected make it less likely that the Minocin will reduce its effectiveness?

Thanks,

jasrich

^{11/26/08 Igenex positive}

^{Current Rxs 12/17/08: Levoxyl 100mcg, SRT3 5mcg BID, Klonopin .5mg, Seroquel 12.5mg, Ibruprofen PRN (daily), Acidopholus/Bifidus, digestive enzymes, vits B-50, B5 500mg, B-12 1cc 2x/week, Lithium 5mg}

kitty9309

Regular Member

Joined : Oct 2008

Posts : 163

Posted 12/29/2008 12:20 PM (GMT -7)

The fact that it is an injection won't change how it works against the bacteria.

Found this:
Minocin (minocycline) and penicillin G benzathine-penicillin G procaine (penicillin) (Moderate Drug-Drug)

GENERALLY AVOID: Tetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by penicillins. Antagonism is more likely when low doses of either agent are administered. Therapeutic failure may result.

MANAGEMENT: This combination should be avoided if possible.

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