Hi Ticker, I've had many AM cortisols done - last was last week and it came back at 13.6 with a range of 4-22. I did saliva labs last year and they came back somewhat depressed for AM and 5PM, normal for noon and 11PM. That's what got me started on treating my adrenals with glandulars and then hydrocortisone (HC). Of course, now I know that HC was probably a big mistake if I have Lyme. I'm now supplementing with licorice root extract and looking for a good adaptogen blend to support the adrenals.
When I originally asked my endo to give me Armour he refused and gave me 5mcg of Cytomel instead and reduced my T4 from 125mcg to 112mcg. I did not do well on the combo - it really fired up my GI SX, made me anxious and made insomnia worse. I also sweat a lot. In hindsight, that's the same reaction that I have had every time I have tried to add anything with T3 to my regimen, including Armour and SRT3 (several different dosages). Posting about this on some thyroid forums I was told that T3 is hard on the adrenals, have I had them checked, done saliva testing, taken HC, etc., and that's what started me down the path of trying to find docs that would RX HC. Recently I have tried the following (RX'ed by either my endo or my integrative med doc/LLMD)
Dropping the T4 and just taking 22.5mcg of SRT3 BID - crashed and burned, horribly hypo, freezing cold, tired but couldn't sleep, depressed;
100mcg of T4 + 5mcg of SRT3 BID - pretty much the same result as above;
112mcg of T4 + 5mcg of SRT3 BID - same;
125mcg of T4 + 5mcg of SRT3 BID and then reduced SRT3 to 2.5mcg BID - this was more like the Cytomel - GI got bad, more anxious, worse insomnia, and, a new SX, hands aching horribly like over-night arthritis in addition to my usual back, knee, etc pain. The difference here is that I started this a couple of weeks after I finished the month trial of ABX for Lyme so maybe some of the SX, and especially the aching hands, was herx. At least that's what my LLMD thought.
So, I stopped with the SRT3 for now and went back to just T4 (137mcg) so that I can get relatively stable before my big adventure at the Cleveland Clinic in two weeks. My last labs were:
TSH: .5 (with a range of .4 - 4) and FT4 1.76 (with a max of 1.76). I asked for a FT3 but the endo ordered a total T3 instead (typical) and it came back at 118 with a max of 300 something (don't have them in front of me). With my TPO-ABs, there's very little doubt that I have Hashis. I just wonder how much worse it is now since I did the year on HC and the Lyme has gotten worse.
I was on vitamin D but LLMD took me off of it b/c he believes in the Marshall Protocol which says that D is bad. I've tested low for it every time except for after I had been supplementing it for a few months. Since I'm not doing the MP maybe I should start it up again. I intend to ask Dr. J about it when I see him in March.
I'm told that Dr. J doesn't test for the co-infections but he treats for all of them. Are you saying that I should go ahead and get them done anyway?
jasrich, you are lucky to have Northlover as your sister!
I agree that most doctors will not run these tests which are more important. Was the corisol testing you had done blood testing? Can you post the ranges for your results? You may want to consider having saliva testing done. Some doctors believe this is more accurate, some do not.
There is room to increase your Free T3. It seems like you may do better adding a T3 only med, such as Cytomel, so that you do not further increase your Free T4. What dose did you start on? Maybe it was too high to start with. As far as I know, positive antibodies--and yours are very positive--indicate Hashimoto's.
Being Vitamin D deficient can cause a lot of symptoms. I suggest reseraching this. I believe if somone is deficient, they should supplement. This is only my opinion. Many people who have Lyme are Vitamin D deficient.
You may want to consider having the co-infection testing done before your appointment with Dr. J. It typically takes about three weeks to get the results and then you would have them for your appointment.
I was not diagnosed with Hashimoto's until after I was diagnosed with Lyme; however, thyroid problems run in my family.
Lyme disease can definitely affect multiple systems of the body. It is important to have all of these things checked so you can get individualized treatment that will most benefit your case. It seems overwhelming, but it can be managed!
11/26/08 Igenex positive
Current Rxs 12/17/08: Levoxyl 100mcg, SRT3 5mcg BID, Klonopin .5mg, Seroquel 12.5mg, Ibruprofen PRN (daily), Acidopholus/Bifidus, digestive enzymes, vits B-50, B5 500mg, B-12 1cc 2x/week, Lithium 5mg, fish oil 1500mg/day