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C4a anf C4c?

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Lyme Disease
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Dowa
Veteran Member
Joined : Sep 2008
Posts : 1120
Posted 1/22/2009 1:52 PM (GMT -8)
Hi Guys: Do any of you know the difference between c4a and C4c? Here at the clinic they testC4c (complement component) Do any of you know what the difference is between the C4c and C4a?? Thanks  D
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LupnerRN
Regular Member
Joined : Sep 2008
Posts : 350
Posted 1/22/2009 3:09 PM (GMT -8)
I haven't heard of either,

I'll look it up. What do you know of them?

best of luck at the clinic!
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LupnerRN
Regular Member
Joined : Sep 2008
Posts : 350
Posted 1/31/2009 3:46 PM (GMT -8)
I saw my LLMD wednesday and asked about this test.
She said it's specific for inflammation, more sensitive than a ESR, which we would all have in varying degrees. So it's not real necessary. She doesn't consider it a treatment tool.

Then I just read from Dr. Schaller, that CD57 is good for lyme but not C3a, C4a.
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Dowa
Veteran Member
Joined : Sep 2008
Posts : 1120
Posted 1/31/2009 3:55 PM (GMT -8)
This is SO confusing, the doctor here would not even consider doing the CD57 for me, said it wouldnt tell us anything. Makes you crazy doesnt it?? (:  D

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LupnerRN
Regular Member
Joined : Sep 2008
Posts : 350
Posted 1/31/2009 4:37 PM (GMT -8)
Yes! it does make me crazy.
Like my brain doesn't have enough issues to deal with right now.

My doc doesn't think CD57 is that useful either, that it's interesting but can't really help you decide when to stop treatment or not. She focus' on the symptoms and say's "as you know, you can't rely on tests" and I do agree with her.
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Tallison
Regular Member
Joined : Jun 2007
Posts : 417
Posted 2/1/2009 8:32 AM (GMT -8)

Hi!  Do you mean C3a and C4a complement levels?  You can do a search on here and find a lot on them.  It was useful for me at one point because most of my labs were testing normal.  And then suddenly I got a reading of I think 26,000 for my C4a (it shouldn't be over 2800).  Dr. Shoemaker has done research on these levels, you can do an online search and see videos of him talking about it, how it corresponds with mycotoxin levels and correlates with HLA genotypes (that is, genetic testing).  So for me, it makes sense that I have a hampered ability to create antibodies to mold (as discovered in my HLA testing).  It told me that I needed to test my current environment for toxins. 

C3a and C4a reportedly can identify if you are struggling with Lyme disease or other mycotoxins such as mold.  There are many things that reportedly can help to lower these levels. 

HLA testing can be helpful too.

Tracy

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Dowa
Veteran Member
Joined : Sep 2008
Posts : 1120
Posted 2/1/2009 10:09 AM (GMT -8)
Tracy: If you look at my post, the question was what is C4c??  I know it is a complement and thats all I know. Do you know what it relates to?  My result was low not high. Like I said, it makes me crazy. (: Hard to figure all of this out and what it all means. Thanks  D

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Tallison
Regular Member
Joined : Jun 2007
Posts : 417
Posted 2/1/2009 10:36 AM (GMT -8)
I know! It drives me crazy, too. Not sure about C4c, don't think any doc has tested me for that. I'm curious as to what type of doc you are seeing. Tracy
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Dowa
Veteran Member
Joined : Sep 2008
Posts : 1120
Posted 2/1/2009 12:04 PM (GMT -8)
Environmental medicine. He tested me for that after a toxic-mold exposure. Found out about the Lyme later.   D

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