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Regular Member

Date Joined Feb 2006
Total Posts : 346
   Posted 2/4/2009 9:00 AM (GMT -6)   
Hello - wondered if you had any thoughts on my treatment at this point.

Biaxin + plaquinil bid + Spronox

Bicillin IM 1/week - 1st injection yesterday and it didn't hurt much at all.

I have read that some people do as many as 3 per week and my concern is that the drug concentration of the Bicillin will not be high enough.

Previously on 13 months IV with Plaquenil every day
1 months IV Roceph + Mepron + oral Zithro. Couldn't get rid of Babesia & neuro Lyme not improving.
7 months IV Zithro + IV Roceph 3/wk
3 months IV Zithro + IV Roxceph 3/wk + IV Clindi bid - adding the Clindi made a huge difference in my lower leg tissue and bone pain.

Off IV's and any antibiotics for Dec. Started Sporonox and tested neg for yeast, c dif., etc.
Jan. started up Biaxin with Plaquinil and Sproronox. Slow return of leg pain and some body aches and pains, headaches. Now the leg pain and neuropathy is really increasing. Functioning about 80% which is a big improvement from about 20%.

Again, is the 1 injection per week enough? I have wondered if doc is taking a low dose, slow kill approach - so to speak.

Thanks for any input.

Veteran Member

Date Joined Sep 2008
Total Posts : 1120
   Posted 2/4/2009 3:12 PM (GMT -6)   
Beth: You must have found someone to do your shot? Or did you learn how? Good luck with the treatment.  D

Regular Member

Date Joined Feb 2006
Total Posts : 346
   Posted 2/4/2009 3:25 PM (GMT -6)   
Hi Dowa,

How are you? Yes, my husband did the first one yesterday and it was a piece of cake as long as you let the injection come to room temp (it is the thickness of glue!).


Regular Member

Date Joined Feb 2006
Total Posts : 346
   Posted 2/5/2009 11:25 AM (GMT -6)   
I forgot to add that the dosage for the injections is 1,200,000. From what I read it does stay in the system up to 14 days so maybe it is enough to have it 1 per week. Those who were getting up to 3 per week may have been on lower doses?

I also do not want to minimize the serious of the injection. The precautions are scary but those living with the effects of lyme seem to be strong people?

Thanks again,

Veteran Member

Date Joined Aug 2006
Total Posts : 1161
   Posted 2/6/2009 12:13 AM (GMT -6)   

I think you will do fine with the 1 shot per week of bicillin.

It is good that you are on biaxin now. In my opionion, it is one of the most effective oral meds in the lyme world. It affects many different creatures, some more than others.

With the addition of plaquenil, you are covering even more. The leg pain you are experiencing is most likely a herx. Some often see this in the leg that had "the restless leg feeling" before treatment started. You will sometimes get this pain more in one leg versus the other. It is very hard to say what is affecting what with your combination. And any of the 3 B's could cause the leg pain, whether it be borrelia, babesia or bartonella. Some theorize that plaquenil makes the biaxin penetrate better. That is just a claim as far as i'm concerned. I won't go further into it, nor do i embrace the idea. Nothing is proven with the plaquenil ph lower effect idea.

But plaquenil is a mild/medium antimalarial and has some decent anti-inflammatory properties. Biaxin also has some slight antimalarial properties. Biaxin also has an effect on lyme and most likely bartonella.

Biaxin by itself isn't the most exciting thing. You can combine it with many other different drugs and get all sorts of different results. It was always the main tool in my past treatment for bart and lyme.

Some of my favorite biaxin combinations for lyme and bart was:





or Biaxin/Amoxicillin

Also, i'm not a huge fan of the sporanox your dr has you on. That stuff is a little creepy if you ask me. It is getting up there in toxicity. Not as nasty as lamisil(the nastiest of all antifunguls) but getting close. I think you could do just fine with a small dose of Diflucan plus oil of oregano and olive leaf extract. Much safer in my opinion. Your dr must have something against diflucan.

Well good luck. Don't let go of the biaxin. It is good stuff.

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