I got a blood clot 36 hours after I got my PICC. I had a lot of pain from the underam/shoulder area right into my heart. My upper arm was very swollen though I did not realize that. I was short of breath and had chest pains.
When my IV nurse came for the "day after" visit, she sent me right to the ER. They did an ultrasound, found the blood clot, and promptly pulled my PICC.
For now I am just using heplocks. They have to be changed every week. My IV Rocephin hurts like heck going into the vein in my hand. I am supposed to see a hematologist to be worked up for clotting issues before my LLD will order another line. I am working on that.
I am terrified to get another PICC and usually nothing scares me.