Yes, itching from either cause may respond to Zyrtec. Itching is usually a histamine response. As long as you don't get airway constriction or a rash, I'd guess you're ok for a few days while waiting to talk w/ your doctor about this, but you might also want to talk w/ your pharmacist about the medications you are taking to see if they have any insights on what's causing the itching. I hope this helps - take care,
Chronic Lyme Disease, Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, Anemia, Lymphopenia, intermittant Pancytopenia, chronic malabsorption/malnutrition, etc.; G Tube; Currently TPN-dependent.
Meds: Zofran, Pulmicort, Heparin (to flush PICC line), IV Cipro (for G-tube site infection).