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Regular Member

Date Joined Aug 2008
Total Posts : 62
   Posted 3/11/2009 3:31 PM (GMT -6)   
I got a copy of my labs today and I was wondering what C4 and C3 are. My C4 was almost double the normal range and my C3 was about 100 points under the normal range. I tried searching and see a little about arthritis maybe? I am confused. Anyone know about this?

Veteran Member

Date Joined Sep 2008
Total Posts : 1120
   Posted 3/11/2009 3:53 PM (GMT -6)   
As far as I was told when I asked, they have to do with inflammation in your body. Others here will be able to tell you more..  D

New Member

Date Joined Mar 2009
Total Posts : 15
   Posted 3/28/2009 11:11 PM (GMT -6)   
Minx, I had my C3 very low and I was diagnosed with Babesia yet negative for Lyme.

I was told by my intial doctor that a low C3 and C4 could be a autoimmune condition such as Lupus.

Yet just read this article regarding a suppressed C3 and C4 with Babesia, yet do not know if this will be the same response with Lyme.

Regular Member

Date Joined Aug 2008
Total Posts : 62
   Posted 3/29/2009 10:37 AM (GMT -6)   
Hi Nexis

Thanks for your response and the link. I have not tested positive for Babesia and my LLMD is not sure I have it (clinically). Although, I have to say autoimmune is right up my alley. During my last two herx's, I had sharp pains where my sternum and ribs meet and initially thought Lupus, but it went away in a few days and nothing else - thank goodness. Once my friend got Minocin-induced (taking for acne) Lupus and I remember her having a similar pain. It took her a year to recover. I am taking Minocin right now.

This is what I have come up with so far on my own.

Decreased C3 can mean susceptibility to bacterial infection.

Increased C4 is a mediator of local inflammation and can be associated with autoimmune or mold.

I also read about something about low C3 and kidney damage, but I have not looked into that any more.

I just tested very low on a cortisol test and just started supplementing so maybe that will help with the C3.
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