Yep, have been on plaq and biaxin for 4 months now and it's a wonder combo. The sideaffects, though minor, can be annoying. For me they are stomach issues, which can be mitigated by taking pills on a fully full stomach, achne, and the dreaded herxes. Also with plaq, you will need to get periodic eye exams, as it rarely builds up in your retina(s). The herxes come every 3 or so weeks. For me they are gradually becoming less severe over time.
In short, I love this stuff.