Mepron needs to be taken with fatty foods because it increases the absorption of the medication.
This is from Drugs.com
under the heading of "How to use Mepron"-
Take Mepron by mouth with food or meals. The medicine may be less effective if it is not taken with food. If possible, include foods with a high fat content (eg, whole milk, cheese, ice cream, eggs, fried foods). www.drugs.com/cdi/mepron.html
Hope this helps!!