DGL (de-glycyrrhizinated licorice) is often used to treat heartburn - it tightens the Lower Esophageal Sphincter so that stomach acid can't wash backwards up the esophagus and cause the heartburn.
Also, if you have H. Pylori infection, it can be treated with mastic gum and myrrh gum quite successfully. I got rid of mine this way...
Nexium, Axid, and related medications only mask the symptoms of heartburn by reducing the acidity of the stomach. This opens you up for infections in the stomach, since stomach acid kills some bacteria & other critters. Also, there is an increased risk of developing food allergies and nutritional deficiencies (Vitamin B12, iron, calcium, etc. - any nutrient that requires stomach acid for absorption) in those on long-term acid reduction medications.
I hope this is helpful - take care,
Chronic Lyme Disease, Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, Pancytopenia, chronic malabsorption/malnutrition, etc.; G Tube; Currently TPN-dependent.
Meds: Zofran, Pulmicort, Heparin (to flush PICC line), IV Ceftazidime (for Plural Effusion).