No, do not stop the abx. Your thumb needs treatment. Try to reach the LLMD's office and ask to speak with the nurse about it - nurses are usually able to get answers back to you more quickly than if you just try to reach the doctor.
I don't think it would mess up the Lyme test...I'm not aware of Trimeth/Sulf being used to treat Lyme...
Chronic Lyme Disease, Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, Pancytopenia, chronic malabsorption/malnutrition, etc.; G-Tube; Currently TPN-dependent.
Meds: Zofran, Pulmicort, Heparin (to flush PICC line), Claritin, Colloidal Silver (used topically), IV Milk Thistle, probiotics.