Difference between Igenex IGG and IGM

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Regular Member

Date Joined Aug 2006
Total Posts : 293
   Posted 6/4/2009 6:33 AM (GMT -7)   
What do these two tests mean?  I was positive on the IGM and negative on the IGG.  I thought that one means current infection and the other past infection?  I do not know what to think, thanks.

Veteran Member

Date Joined Feb 2003
Total Posts : 9208
   Posted 6/4/2009 10:02 AM (GMT -7)   

Hi momtothree.  The IgM shows a more recent infection and the IgG shows a longer-standing infection.

Many people who have Lyme do not have a positive Western Blot.  The CDC requires several bands to show for it to be positive.  Lyme doctors often focus on which Western Blot bands are positive--some are specific for Lyme.

Regular Member

Date Joined Aug 2006
Total Posts : 293
   Posted 6/4/2009 12:14 PM (GMT -7)   
I am not CDC positive but Igenex positive.  The bands I have positive are:
18 kDa ++
30kDa +
34kDa +
41 kDa ++
58 kDa +++
83-93 kDa +
Do you think that these positive bands are significant for Lyme and should be treated as such?  I had Lyme from 2006 to 2008 and the Igg was negative.  So, I gess that means that I have been reinfected???? Doctor thinks I have Bartonella but says it is not worth testing since there are 22 strains and the test only covers two.  Your thoughts would be appreciated.   Thanks.
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