Question about Western Blot Results

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New Member

Date Joined Jun 2009
Total Posts : 3
   Posted 6/24/2009 3:02 PM (GMT -7)   
I have been having numbness/tingling in extremities as well as difficulty concentrating, brain fog for the past 4 months. As part of a MS work-up I had a Lyme test performed. The only thing that came up abnormal was IgG P41 ab...everything else was normal. The results seem to say that you should have 5 positive bands for a positive Lyme test. Can anyone explain the results to me? So, does this mean I've been exposed to Lyme at some point or not? Should this be pursued or does it mean I don't have Lyme?

Thank you!

Veteran Member

Date Joined Jul 2006
Total Posts : 652
   Posted 6/24/2009 3:10 PM (GMT -7)   
Band 41 can indicate lyme exposure, but it can also show up as a cause of being exposed to or having other bacterias in the body. You should find an LLMD (a lyme-literate medical doctor) and get another test done through Igenex Labs in California. This is a more sensitive test and their standards are not as strict as the CDC.

If you need help finding a doctor to test you, just let us know where you're at and we will do our best to help!
Current treatment (began June 10th 2009):
Biaxin 1000mg/day, Pulsing Flagyl 500mg/day 1 Week Every Month

New Member

Date Joined Jun 2009
Total Posts : 3
   Posted 6/24/2009 3:24 PM (GMT -7)   
I'm in San Antonio, TX...any recommendations?

Veteran Member

Date Joined Jul 2006
Total Posts : 652
   Posted 6/24/2009 3:55 PM (GMT -7)   
I know of a doctor in Dallas. Is that too far?
Current treatment (began June 10th 2009):
Biaxin 1000mg/day, Pulsing Flagyl 500mg/day 1 Week Every Month

New Member

Date Joined Jun 2009
Total Posts : 3
   Posted 6/24/2009 3:59 PM (GMT -7)   
That's about 5 hours away...that would be great if you could give me the info.

Veteran Member

Date Joined Jul 2006
Total Posts : 652
   Posted 6/24/2009 4:05 PM (GMT -7)   
We can't post doctor names on here, so if you want to tell me your email address, I'll send you the info.
Current treatment (began June 10th 2009):
Biaxin 1000mg/day, Pulsing Flagyl 500mg/day 1 Week Every Month

Veteran Member

Date Joined Feb 2003
Total Posts : 9208
   Posted 6/24/2009 6:17 PM (GMT -7)   

Hi emmas1, welcome to the board!

There is no completely reliable test for Lyme, and results can vary by lab.  On the Western Blot, the CDC requires several bands to be positive for the test to be positive; however, many people who have Lyme do not have this many bands.  Which lab did your test?  Labs such as Quest and LabCorp do not list all the Lyme-specific bands that IgeneX Lab lists.

Below is a Lyme symptom list.  You can have any combination of symptoms. 

Unexplained fevers, sweats, chills, or flushing
Unexplained weight change--loss or gain
Fatigue, tiredness, poor stamina
Unexplained hair loss
Swollen glands
Sore throat
Testicular pain/pelvic pain
Unexplained menstrual irregularity
Unexplained milk production: breast pain
Irritable bladder or bladder dysfunction
Sexual dysfunction or loss of libido
Upset stomach
Change in bowel function-constipation, diarrhea
Chest pain or rib soreness
Shortness of breath, cough
Heart palpitations, pulse skips, heart block
Any history of a heart murmur or valve prolapse?
Joint pain or swelling
Stiffness of the joints, neck, or back
Muscle pain or cramps
Twitching of the face or other muscles
Neck creeks and cracks, neck stiffness, neck pain
Tingling, numbness, burning or stabbing sensations, shooting pains
Facial paralysis (Bell's Palsy)
Eyes/Vision: double, blurry, increased floaters, light sensitivity
Ears/Hearing: buzzing, ringing, ear pain, sound sensitivity
lncreased motion sickness, vertigo, poor balance
Lightheadedness, wooziness
Confusion, difficulty in thinking
Difficulty with concentration, reading
Forgetfulness, poor short term memory
Disorientation: getting lost, going to wrong places
Difficulty with speech or writing
Mood swings, irritability, depression
Disturbed sleep-too much, too little, early awakening
Exaggerated symptoms or worse hangover from alcohol

When Lyme disease is a possibility, it is very important to see a knowledgeable doctor.  Many doctors do not understand Lyme and treat with outdated protocols.  Besides Lyme, ticks can also transmit several co-infections including Babesiosis, two types of Ehrlichiosis (HME & HGE), Bartonella, and Mycoplasma.  Many people who have Lyme are co-infected.  It may affect treatment choice and progress.  It is important to be tested for these by a Lyme reputable lab such as IgeneX in Palo Alto, CA.  Have you been tested for these? 

If you need a doctor recommendation, you can email me at  

It is also important to learn as much as possible.  I recommend reading Dr. Joseph Burrascano's 2008 Diagnostic Hints and Treatment Guidelines For Lyme and Other Tick Borne Illnesses at  He is one of the top Lyme doctors in the country, and many Lyme doctors follow his protocols.   I also recommend the books "Everything You Need To Know about Lyme Disease Second Edition" by Karen Vanderhoof-Forschner and "The Lyme Disease Solution" by Kenneth B. Singleton M.D.

I hope you can get answers soon.

Veteran Member

Date Joined Apr 2009
Total Posts : 1013
   Posted 6/24/2009 8:39 PM (GMT -7)   
Hi emmas1,

CG is most likely close to you and i bet she would be glad to help you find a LLMD. i am sure its way closer to go to La. then dallas.

I'm outside of amarillo Tx and there isnt one near me either. i wish you all the best
still looking for answers

Veteran Member

Date Joined Aug 2007
Total Posts : 887
   Posted 6/25/2009 7:40 AM (GMT -7)   
Emmas1, From what I've read on this board, the doctors in TX don't think you have LD in Texas.  It would be best if you saw a LLMD if you have alot of the symptoms from Ticker's list to be sure you are tested properly.  Take Care, KO
2001 symptoms started:
Tingling in fingers and toes both sides, not tested at that time for LD
2007 Summer tested pos. WB, diagnosed with LD, tested neg for co-infections thru Igenex
Abx - Doxy 100mg 2x/day for 3 weeks (before diagnosis)
Amoxicillin 1gm 2x/day for 1 month
Amoxicillin 1gm 3x/day with Probenecid 500mg 2x/day  5 months 
Currently on Dr. Zhang's protocol stopped Zhang's after 6 months symptoms returned.  Started Buhner's protocol May 2009

Veteran Member

Date Joined Mar 2009
Total Posts : 4717
   Posted 6/25/2009 11:26 AM (GMT -7)   

Hi, I am from Louisiana and we have an LLMD here. I'm not sure how far away he would be from you, but if you'd like the info, email me. You can click on my name to the left or click on the envelope.
2003 symptoms started;panic attacks,anxiety,heightened senses.
2007 Diagnosed with Lyme. Didn't start treatment.
2008 symptoms came back with a vengence.
2009 Diagnosed with Lyme plus co-infections....Babesia and Bartonella.
Illnesses:-Chronic Lyme Disease,Hashimotos Thyroiditis, Ulcers, Hypoglycemia
Medications:-Biaxin 250mg to start,Mepron,Ultram,Thyro Complex 60mg,Probiotics and supplements

Veteran Member

Date Joined Apr 2009
Total Posts : 1304
   Posted 6/25/2009 7:57 PM (GMT -7)   
Killer, as I said on your other post about 39, it sure does appear you have lyme for sure if you have bands 41 and 39. But I'm no LLMD. This is based on all the research I could find on the WB and the bands.
Lyme in NC in 1971? Suspect TBI: Fully engorged tick followed by high fever and tonsillitis. Follwed by , lumps on neck,  chronic tonsillits w/ constant low grade to recurring high (104) fevers, severe unexplained neck stiffness and acute neck pain.   Followed by tonsillectomy, urinary tract infections, miscarriage, appendicitis while pregant, chronic severe back pain. Followed by depression, mild anxiety, mitral valve prolapse, and hypglycemia.  Was this a TBI??
Bit again couple of times, lyme suspect bite Mother's Day 2007. Bite, symptoms, lyme specific antibodies on the most lyme specific band of all = 39 IgG.  Still awaiting appt w/ LLMD.

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