High serotonin levels?

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Amy C
Regular Member

Date Joined Jan 2009
Total Posts : 45
   Posted 7/31/2009 12:49 AM (GMT -7)   

Just wondering if anyone else has high serotonin levels? 
The normal on the test I took is between 100 and 225 and mine is 305.

I don't take any meds that I think would cause this.

I thought I read online it can cause anxiety, insomnia, and low metabolism to name a few. I do have all of those.

Just thought it was worth a discussion. Any else?

One BIG Lyme family!! Possibly congential...
~I tested CDC positive 10/08
~My mom Igenex positive 11/08
~My brother Igenex positive 4/09
~My 2 boys some positive & IND bands, clinical diagnosis 3/09
~My youngest has Aspergers too (a form of autism)

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Date Joined Sep 2008
Total Posts : 1120
   Posted 7/31/2009 4:29 PM (GMT -7)   
From what I have read, the symptoms you list are normally from LOW seratonin. Interesting that yours is high, all the Lymies I know have lower than normal levels. Mine is about 50, I was told to take tryptophan, to make more seratonin.  D

New Member

Date Joined Aug 2009
Total Posts : 1
   Posted 8/20/2009 5:02 AM (GMT -7)   
 Hey guys, please let me know if you find anything else out about this issue.  My serotonin level tested at 320, which is a lot higher than it should be.  I do have problems with my appetite, and have had chronic diahrrea for the past 7 months.

Regular Member

Date Joined Jan 2009
Total Posts : 376
   Posted 8/20/2009 9:04 AM (GMT -7)   
Could it possibly be Serotonin Syndrome?
The article shows some possible bad drug combos.  Like taking tramadol and an SSRI.
Lyme, anxitey, depression, chronic C. Pnuemoniae
"... expect the unexpected ..."  (O. Wilde)
"I am an old man and have known a great many troubles, but most of them never happened." (Mark Twain)

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Date Joined Feb 2014
Total Posts : 675
   Posted 11/24/2017 2:19 PM (GMT -7)   
I didn't know there was a test for measuring serotonin levels. What is its name?

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Date Joined Mar 2014
Total Posts : 6201
   Posted 11/24/2017 2:31 PM (GMT -7)   
Hi xy123

This is a pretty old thread - originated in 2009 so most people in the discussion are no longer visiting this forum very frequently.

But maybe others will chime in?

Serotonin is a neurotransmitter. I good test is a 24-hr saliva test with 4-5 saliva samples and a urine sample for cortisol levels. Most naturopath doctors are familiar with how to test and supplement.

Hope that's helpful -


Chronic late-stage lyme—likely infected in '98; Clinically dx Mar'14 w/ Babs, Fry Labs+ Bart-like, CDC+ Bb. First treated 4-5 viruses, GI/immune. Herbal antimicrobials in May; IV port-started Rocephin in Nov; added vancomycin Mar'16;
DETOX: Pinella/Burbur/Parsley/Milk thistle/Burdock/Red root; Samento/Banderol/Enula; JK/Turmeric; BFM-1; antifung; many supps; cholestyramine

Veteran Member

Date Joined Feb 2014
Total Posts : 675
   Posted 11/24/2017 2:49 PM (GMT -7)   
Hi Pirouette, thanks for responding. Are the others in this thread talking about the 24 hr saliva test you've pointed out or an other kind of test?

Regular Member

Date Joined Oct 2014
Total Posts : 168
   Posted 11/24/2017 3:14 PM (GMT -7)   
Our doctor's office just gave us a hand-out Serotonin Syndrome, last week (link 1 below.)

Reason being our DD was at a slightly increased risk for SS due to taking two RX that could cause this outcome.

I know you said you weren't taking any RX that could cause this possible outcome but ,just in case (once a mom always a mom), herbals and over the counter cough and cold meds can also be a cause.


Interesting, this website states at the bottom that elevated serotinin levels can be caused by dumping syndrome

"Dumping syndrome - Symptoms such as nausea, cramping, sweating, and weakness that may occur when the stomach contents are emptied rapidly into the small intestine before being digested; may occur in patients who have had gastric resections or bypass surgery"

Just interesting because so many of us have GI issues, like yourself. Take out the gastric/bypass part and it is possible the stomach is emptying too fast.

But I am not a doctor. So, I don't anything. Just a gal doing a little research on the side.

Big warm hugs for healing and answers -

Peppermint Tea

(link 2)

Regular Member

Date Joined Oct 2006
Total Posts : 356
   Posted 11/25/2017 10:20 AM (GMT -7)   
My serotonin tests abnormally high by saliva test.

No one has answers for me.

I have anxiety and can't sleep without pills. I'm never drowsy.

I don't have dumping syndrome symptoms.

Wish I knew why. Could zolpidem cause this?

Veteran Member

Date Joined Mar 2014
Total Posts : 3986
   Posted 11/25/2017 10:34 AM (GMT -7)   
K- With all we go thru- your anxiety is most likely caused by several combined things going on.

You might have high cortisol as well and "toxified" methalation from not detoxing or the inability to do so from genes or all the die off if your currently killing the critters in you.

Even if this high serotonin is the cause, it might be temporary, and the use of calming adaptogen (adrenal) herbs and just regular calming herbs (make you drosy) might cover this enough to get to sleep.

Ever get a 24hr saliva Adrenal test? ZRT labs $150.

Seldom is anxiety one cause. Even with non-lymies, neurotransmitter issues are a combo of genetic methalation gene issues there physical environment (sun) and some mental environment (people they are near).
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