I took it before I was diagnosed for tendinitis. When I was diagnosed I had been taking it for 6 months for the tendinitis. My CD57 was 76 that was before starting any treatment. I just had another CD57 done after 6 months of Zhang's protocol and it was 34. I believe the Cat's Claw was responsible for raising my CD57 the first time (It is known to raise the CD57 score). I am now on Buhner's protocol which has Cat's Claw as part of the core protocol.