Does anyone experience evening fever and chills? My husband has been on treatment for one year now and is currently on Rocephin and Flagyl. He has had several episodes that ended him in the ER. Almost the same time each evening he gets elevated temperature between 100.5 and 102.9 with chills sometimes so severe his bed actually shakes from his shivering. Sometimes breathing becomes labored. It passes within 2 hours. During his last visit to the Er they decided to keep him for a couple days due to the breathing problem. They continued his meds during his stay and no reactions to them while he was there. The hospital of course does not believe it is Lyme disease and sees only the ALS dx and sends him home with no further testing. LLMD does not believe it is from meds because when he went off them for 2 days the fevers returned but with less severity. LLMD says go to your primary care doctor. (useless) While in the hospital my husbands primary care doctor was out of town. The doctor taking his calls told me he has seen ALS and is glad we are treating for Lyme. He said he couldn't believe that 1-1/2 years ago that my husband was a strong never ill man. Too quick, he says. Where do we go from here? I am beside myself. He is now on a feeding tube, bi-pap and needs communication device because of his slurred speech.