I've been on Rocephin since 2/25/09 - LLMD wants me on it for one year. Also taking 400mg doxy a day (oral) and 100mg Diflucan - 2 weeks on, 2 weeks off. I started noticing improvement about 4 months into treatment. Physical symptoms much better, neuro symptoms about 50% better. But LLMD told me I will probably pulse with various orals (and Tindemax is one of them to break open the cyst form) for the rest of my life - this may not be the case, but she is preparing me for the worst case scenario. When I first began treatment, my CD-57 was 16; last month, it was 42! So, while it's still below the norm of 60-300, I am improving, albeit slowly...but it is such an improvement from where I was in February.
Best of luck & Hugs,