Thanks everyone for your input.
Hope_29 & Sunshine 20090909
I will give you some info on Brucella and if you have more questions just ask I will try to answer them (I don't have all my info in front of me right now)
My daughter will be starting the treatment of Doxy 100mg + Rifampin 300mg twice daily (to get at Bart and lyme too) She is 12 yrs old.
Children under 8 yrs usually are given Bactrim/Septra + Rifampin
Optimal treatment is -- Combination therapy: Doxy + Streptomycin (or gentamincin)--these are intramuscular injections
or Triple therapy : Doxy + Streptomycin + Rifampin
Doxy + Bactrim/septra + Rifampin
Using other antibiotics and not treating long enough has a high relapse rate.
Well, we live on a farm and have horses, dogs, cats and she was always outdoors or with them. (Started to notice symptoms of whole mess 2005)
I am not totally sure how she got it but it can also be transferred by ticks (brucella occurs in wild animals too), or actual animals although not much is said about it. Things you read about it try and make it sound like you only get it from drinking unpasteurized milk and cheese etc. and its rare and only in 3rd World countries.. That is why I think LLMD's need to get up to speed with it, because I think a lot more people with Lyme and coinfections have it and don't know and it's never checked. Probably a factor why not getting better after a certain point.
Her fever also is usually highest in the morning. (reverse pattern)
I had her tested 3 times: 1st & 3rd-- Quest Labs: Brucella IgM IgG (Can do Febrile Reactions Panel which includes Brucella, if checking other things that cause fever
also incudes Weil- Felix Test which checks for Proteus OX19, OX2, OK
which if positive can be an indicator to support Brucella even
though negative but low titer present, because only positive with
Rickettsial Diseases, Brucella, Salmonella(Typhoid Fever),Proteus
Vugaris (first time did panel and third just Brucella and Weil-
She was showing up on Proteus OX19 and OX2 , Low titer on Brucella IgM & IgG and positive on Salmonella (typhoid Fever)
2nd Time -- Clongen Lab: Brucella PCR (came out negative)
3rd Time -- Quest IgM, IgG Positive both Brucella IgM & IgG, and Proteus Ox2 , Salmonella(typhoid Fever) all Negative
If cultures are done they have to be left for many weeks, that is probably the test you were told takes 6 wks.
I think Fry labs also tests for Brucella (they had a Febrile Panel) and MDL I think has a PCR
I think you are right about that you should not have antibodies for it unless you contracted it at one point or are carrying the disease (chronic). Known to relapse. Just as complicated as everything else. I totally agree, what is practiced about having to have a high enough titer to be considered positive, goes against what you read about it. That you can't base it on that! Doctor have forgotten how to piece all the clues and info together figure things out.
Like if having a fever every day that undulates for years isn't a big enough clue. I was my idea to do the tests.
Hope this helps.