In the context of Lyme, it is my understanding that seroconversion from IgM to IgG begins at about 4-8 weeks after initial infection. However, if the initial infection is not treated adequately, one will likely continue to make IgM antibodies to Lyme (if the immune system is functioning adequately) and therefor conceivably could lead to the generate new IgG antibodies after these IgM antibodies are sero-converted. This, along with the fact that Lyme continuously change their outer surface proteins (which means the immune system has to continually generate new antibodies to the bacteria), is why changing bands, whether IgM or IgG, is an indication of active infection no matter how long it has been present.
Chronic Lyme Disease, Chronic Bartonella (clinical dx only), Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, chronic Lymphopenia, etc.; G-Tube; Currently trying to wean off TPN.
Meds: Pulmicort, IV Ceftazidime, Heparin (to flush PICC line), Claritin, Singulair, Domperidone, Colloidal Silver (used topically), probiotics, Milk Thistle, Ailanthus, homeopathy.