What anti-inflammatories would you try for your gut? In your signature, you mention all the usual ones used for UC made you feel worse. I have the same problem from the 5-ASA class of meds (given to me for "Crohn's," which I & my LLND both think is actually gastrointestinal lyme and not Crohn's) - I get rashes or systemic allergic reactions from all of the 5-ASA meds that I've tried.
If I were in your situation, I'd take enteric coated omega-3 essential fatty acid supplements (shown in clinical studies to be as effective for UC as the 5-ASA meds), probiotics (also proven to help UC in clinical studies), and possibly steroid enemas (work best on left-sided UC from what I understand)... Systemic steroids would not be a good idea unless you have no other option. I would also stay away from 6MP/Imuran/Azathioprine, Methotrexate, Remicade, Humira, etc. - these meds significantly reduce the immune system's ability to fight Lyme and other infections.
Another thing that may or may not make a difference for you is reducing consumption of preservatives (specifically sulfite preservatives)...there was a study done in the UK that showed reduced symptoms & flareups of UC in the group that reduced the consumption of red meat and packaged foods containing sulfite preservatives. I don't have the link to the study anymore, but it was very interesting. I know another person with UC who experiences a UC flare when they eat sulfite preservatives.
Chronic Lyme Disease, Chronic Bartonella (clinical dx only), Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, chronic Lymphopenia, etc.; G-Tube; Currently weaning off TPN.
Meds: Pulmicort, IV Doxycycline, Heparin (to flush PICC line), Claritin, Singulair, Domperidone, Colloidal Silver (topically & nasally), probiotics, Liver support herbs, Ailanthus, digestive enzymes, homeopathy.