Yes, GI problems are my most significant issue from Lyme/coinfections. I have motility problems all the way throughout my gut, some nonspecific inflammation, small bowel blockage issues, problems with muscle coordination, and am unable to swallow liquids. My stomach periodically shuts down and I am unable to tolerate any food or drink during an episode. I am still on partial IV nutrition (TPN) because a major attack hit me in 2008 and it has been a big struggle to get my gut back to tolerating anything.
Here is a website with more info on how Lyme can mess up the gut:
Chronic Lyme Disease, Chronic Bartonella (clinical dx only), Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, chronic Lymphopenia, etc.; G-Tube; Currently weaning off TPN.
Meds: Pulmicort, IV Doxycycline, Heparin (to flush PICC line), Claritin, Singulair, Domperidone, Colloidal Silver (topically & nasally), probiotics, Liver support herbs, Ailanthus, digestive enzymes, homeopathy.