Immunoglobulin levels, anyone?

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Regular Member

Date Joined Jul 2010
Total Posts : 34
   Posted 7/22/2010 6:36 PM (GMT -7)   
I asked this in another thread but think it probably better to start a new thread.

Has anyone had these tested and if so what were your results and as far as you know what do they indicate. I know they are an immune system indicator. I'm waiting to hear what my doc has to say about them but wondered if they are relevant in Lyme.

They would be:
Immunoglobulin G, M, A and G subclasses

Thanks much.

Veteran Member

Date Joined Aug 2007
Total Posts : 4399
   Posted 7/22/2010 10:36 PM (GMT -7)   
Total IgG = normal
IgG subclasses 1, 3 & 4 are normal.
IgG subclass 2 is high (above normal).
Total IgM = normal.
Total IgA = very high.

Nobody has been able to explain why I have these results (despite low B & T cell counts), so I've stopped asking...
Chronic Lyme Disease, Bartonella (clinical dx only), Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, etc.; G-Tube; TPN via PICC (trying again to wean off the TPN).
Meds:  IV Cipro, Heparin (to flush PICC line), Singulair, Claritin, Domperidone, Colloidal Silver, probiotics, digestive enzymes, Milk Thistle & other liver support herbs, Magnesium, homeopathy.

Veteran Member

Date Joined Sep 2008
Total Posts : 1120
   Posted 7/24/2010 11:54 AM (GMT -7)   
Interesting Razzle, mine are just the opposite as yours. My T cells (esp. NKiller)  are higher than normal and my IgGs and IgA are low. Wonder what it all means. 

Regular Member

Date Joined Jul 2010
Total Posts : 34
   Posted 7/26/2010 3:37 PM (GMT -7)   
I just wanted to give those that are interested a little update on these Immunoglobulin levels.

I only had very elevated IgG and IgG subclasses. Apparently higher than anyone my doctor has seen. So, I can only comment on these test and know nothing about the IgM or IgA. Apparently very elevated IgG means you immune system is on high alert and working very very hard. It's an indication of a long term chronic infection or it can be an indication of an auto immune disease. While I have Hashimotos and Celiac, both autoimmune diseases, I have a feeling it's the reactivated EBV that's causing these numbers.

Not sure if this helps anyone but thought I would report back.
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