Help with sons lab results

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jilmhny
New Member


Date Joined Sep 2010
Total Posts : 2
   Posted 9/15/2010 7:53 AM (GMT -7)   
Hello, I am new here.   My 6 year old son went undiagnosed for 2 years. Even though i told doctors time and time again i thought it was lyme disease.  His symptoms started 3 weeks after deer tick bite. 
 
I finally changed doctors and he tested postitive for bands 23, 41 and 66 on western blot test through Quest.  My son had a bunch of other test done and dr. told me results showed no coinfections and cd57 look normal.  I recieved the results in the mail and was hoping someone knows how to read it.
 
here they are, sorry its alot of information and i have no clue what it all means
 
 
ANA Rflx Titer and Pattern Negative

B. henselae IgG Screen Negative
B. henselae IgM Screen Negative

B. henselae IgG Titer Not indicated
B. henselae IgM titer Not indicated

E. chaffeenis Ab Interp antibody not detected
E. chaffeensis Ab IgG <1:64
E. chaffeensis Ab IgM <1.20

Anaplasma phag Ab IgG <1:64
Anaplasma phag Ab IgM <1:20

Babesia microti IgG <1:16
Babesia microti IgM <1:20

tTG IgA Ab < 3
IgA      59
Gliadin Antibody, IgA < 3

I can barely see the CD 57 results but i will try to type it as best i can.

CD57+ 3 / 0-19

CD57+ 1 / % of WBC 0-7
CD57I 103 / cells/uL 0-741
CD57+/CD3+ 2 / 0-12
Units: & Lymphocytes

CD57+/CD3+ 1    % of WBC 0-4
CD57+/CD3+ 61   cells/uL 0-468
CD57+/CD8+ 1     / 0-12
Units: & Lymphocytes

CD57+/CD8+ <1     % of WBC 0-4
CD57I/CD8I 46     Cells/uL 0-468
CD57+/CD3+/CD8+ 1     / 0-9

CD57+/CD3+/CD8+ <1      % of WBC 0-3
CD57I/CD3I/CD8I 46       cells/uL 0-352
CD57+CD3-CD8-%WBC     <1
CD57ICD3-CD8-ABSOLUTE + /  <20     CELLS/uL
CD57ICD3 % WBC =    <1
CD57ICD3 ABSOLUTE      23 CELLS/uL

 

 

Any help would be greatly appreciated!

 

 

thanks




Missy Joy
Regular Member


Date Joined Sep 2010
Total Posts : 53
   Posted 9/16/2010 2:40 PM (GMT -7)   
Good grief! That does look confusing! I am sorry I can't help you figure it out though - I am new to this as well. My CD57 results just had one line that said the normal should be greater than 60. Mine was abnormal at 57. Nothing on your results looks remotely like mine.....

I am wondering though if you are taking him to a lyme literate doctor or just a regular family doctor? I have heard that the family doctors are really not up to date on Lyme Disease - and what they consider "normal" is really not.

Hope someone here can help you figure this out!
Philippians 4:13 I can do all things through Christ which strengtheneth me.

jilmhny
New Member


Date Joined Sep 2010
Total Posts : 2
   Posted 9/16/2010 6:03 PM (GMT -7)   
Missy Joy: Thank you for your response! I know so confusing, i cant even find anything online that explains what this all means.

My son is actually seeing a nurse practitioner who is lyme literate but i don't feel he is getting the help he needs. I'm in the process of finding a LLMD. I should have just done that first but i chose the one that was closer to my home.

take care!

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/16/2010 6:53 PM (GMT -7)   

So sorry that your son is sick!  To me, it looks like the tests are within range, but I don't know what some of them are  LOL

I finally changed doctors and he tested postitive for bands 23, 41 and 66 on western blot test through Quest.  
I always tested + for band 23 and 41 on the IgM--only one other band showed + on my IGg.  I have had 6 tests.  What was + on his blot, the IgM or the IgG?  Do you know?

Is he getting treated for lyme?  Please take this disease VERY SERIOUSLY!  I was given 3 wks of abx and it wasn't enough.  Within a couple of months my symptoms came back, very slowly, but surely, including new neurological symptoms.  some days I am almost 100% myself, other days I can't function, I can't even walk, I use the walls and furniture for support to get around the house.  My doc told me that my tests were false + but he was wrong.  He did not treat me for a whole year.  It got really ugly, I could barely walk, think, etc.  LOTS of pain everywhere!  I changed doctors and I am finally being treated.  If it was me, I would have my child on abx for at least 6 weeks.  Bacteria dies in cycles, and you need to kill as much as possible in a cycle, which is about one month. 
 
He has his whole life ahead of him and since you cought this early, he may recover 100% IF TREATED APPROPRIATELY!  Go to a good doctor, you will spend some money now, but it will save you a lot of $$ later, and grief as well.  Tests for co-infections are not reliable, watch and write down ALL symptoms.  My LLMD believes I have bartonella and I tested -- for it.  find a good doctor asap and get him properly treated.  the older the disease, the less chances he'll have to recover 100% AND not relapse in the future.  I don't want to scare you, but please do take it seriously!
 
My thoughts, of course! 

Good luck!

Post Edited (Simela) : 9/16/2010 8:00:20 PM (GMT-6)


madrivergirl30
Regular Member


Date Joined Aug 2010
Total Posts : 205
   Posted 9/17/2010 12:43 AM (GMT -7)   
My understanding is that a titer test is only done if a test is positive, since it's a measure of concentration.

B. henselae is Bartonella, a co-infection of Lyme (a bacteria that causes other illnesses). Many of these tests depend on the presence of antibodies for a positive result; if your body doesn't produce antibodies (which many don't), you will get a false negative.

E. chaffeenis is Ehrlichiosis, another co-infection of Lyme.

Your son's labs would be considered normal: see: http://labs.unchealthcare.org/labstestinfo/e_tests/erlichia_ab_igm.htm

I can help you with the rest if you need help figuring it all out, but I'm really tired at the moment! Follow up with me tomorrow if you don't get the answers you need - the other thing you could do is call the laboratory for a more detailed/layperson explanation.

Post Edited (madrivergirl30) : 9/17/2010 12:55:10 PM (GMT-6)


Razzle
Veteran Member


Date Joined Aug 2007
Total Posts : 4399
   Posted 9/17/2010 6:27 AM (GMT -7)   
ANA Rflx Titer and Pattern Negative -- This is a screening for autoimmune diseases (such as Lupus, Scleroderma, Sjogren's, etc.). The result is negative, meaning your son does not have any of the antibodies associated with these autoimmune diseases. Most LLMD's will run this test, just to make sure there isn't an autoimmune connective tissue disorder complicating the picture.

B. henselae IgG Screen Negative
B. henselae IgM Screen Negative

B. henselae IgG Titer Not indicated
B. henselae IgM titer Not indicated

These are Bartonella henselae tests and since the screening test was negative for both IgG and IgM antibodies, then the titers were not done. Negative results on this test do not mean he does not have Bartonella, it just means the test did not show any antibodies for it. There are a number of different strains of Bartonella, B. henselae is only one strain and not everyone with Bartonella has this strain and so thus it is entirely possible to have Bartonella and not test positive on this test.

E. chaffeenis Ab Interp antibody not detected
E. chaffeensis Ab IgG <1:64
E. chaffeensis Ab IgM <1.20

This is a test for Ehrlichia chaffeensis and because they did not detect the presence of any antibodies to this bacteria (co-infection of Lyme), the test results for this are negative. Again, there are numerous strains of Ehrlichia so a negative test result does not rule out this coinfection.

Anaplasma phag Ab IgG <1:64
Anaplasma phag Ab IgM <1:20

Anaplasma phag. is another variant of Ehrlichia (formerly known as Human Granulocytic Ehrlichia, meaning the bacteria lives inside of granulocytes...these are a type of white blood cell, the most numerous of which is the neutrophil). The test results for this one are negative as well, but again, negative test results do not rule out the possibility of this infection due to the different strains that are out there.

Babesia microti IgG <1:16
Babesia microti IgM <1:20

Babesia microti is one strain of many known Babesia strains. Babesia is a parasite similar to Malaria in that it infects the red blood cells. The test is negative for this particular strain of Babesia, but again, because there are many strains, this test result does not rule out a Babesia infection.

tTG IgA Ab < 3
IgA 59
Gliadin Antibody, IgA < 3

These three tests are done to screen for Celiac Disease. Because the tTG (tissue transglutaminase) IgA is negative, it does not mean the person does not have problems tolerating gluten grains, but it does usually indicate that there is not significant intestinal damage from the consumption of those grains. A person can still have significant impacts on their health from gluten despite negative tTG test results, and there is also the possibility of sero-negative Celiac Disease. Also, Gluten Sensitivity and/or Wheat allergy may still be present in the absence of tTG antibodies.

IgA looks like the total IgA count in his blood, which is needed in order to ensure there is not a deficiency of IgA affecting the other two tests' results...low total IgA would give false negative results on the tTG and anti-gliadin IgA tests even in someone who has severe Celiac Disease. Since there is not a range listed, I don't know what the lab consideres "normal" for this test result...

Gliadin antibody, IgA - this is a test looking for the presence of IgA antibodies to the gliadin (part of the gluten proteins) found in wheat, rye, and barley - i.e., the "gluten grains." This test result is negative for these antibodies, however a person can still have trouble tolerating gliadin/gluten grains if they have a negative test result on this specific test for several possible reasons: 1) sero-negative Celiac (or IgA deficiency, causing artifically low results & thus a false negative on this test), 2) non-Celiac Gluten Sensitivity - need to check anti-Gliadin IgG to look for this, but again it can be sero-negative, or 3) the person has a wheat or gluten allergy, which is mediated by IgE antibodies instead of IgA antibodies...thus an IgE RAST for wheat (should also include rye & barley RAST tests) would need to be done to rule this in/out...

Also, some find they just do better when they do not eat gluten grains, in spite of negative test results...and also it is known that Lyme Disease can cause or trigger problems tolerating gluten that may or may not show up on the tests.

I do not understand the CD-57 results, so am not able to comment on those. I would recommend, however, that you bring these results to an LLMD and ask them to help you understand what they are showing.

Take care,
-Razzle

Chronic Lyme, Bart., Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut dysmotility & non-specific inflammation, UCTD, Osteoporosis, etc.; G-Tube; TPN via PICC.
Meds: IV Ceftazidime, Singulair, Claritin, Domperidone, Milk Thistle, Moducare, homeopathy, etc.
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