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lab results / with referral to infectious disease doctor

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Lyme Disease
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chicksinger
Regular Member
Joined : Jan 2011
Posts : 56
Posted 1/14/2011 4:09 PM (GMT -8)
How to interpret???

Test: Bb antibody screening test (blood drawn on 12/14; results given on 12/30)
Titer/Antibody: PRESENT/Value: 1.18
Positive >1.09

The above are, what I assume, taken from the ELISA results. This is on a CDC reporting form, she did not give him the actual ELISA test result.

--------------
WESTERN BLOT result, not in a form I expected: blood drawn on 1/3 - results obtained 1/14

Pages 2 and 3 of 7:

Lyme Ab/Western Blot Reflex
Lyme IgG/IgM Ab RESULT <0.91 paper criteria reads that NEGATIVE

Lyme Disease Ab, Quant, IgM RESULT: FLAGGED HIGH 1.13 - paper criteria POSITIVE >1.09 being POSITIVE

Under the heading
Lyme Ab, IgM, Interp., EIA Positive Abnormal
All IgG P93, P66, P58, P45,
P41, P39, P30, P28 P23
and P18 All are ABSENT under the Positive header

Lyme IgG WB Interp. - NEGATIVE

Lyme Ab IgM by WB
Igm P41 Ab, P39, P23 All are ABSENT under the Positive header

Lyme IgM WB Interp. NEGATIVE


POSITIVE: 5 of the following
Borrelia-specific bands: 18, 23, 28, 30, 39, 41, 45, 58, 66 and 93
NEGATIVE: No bands or banding patterns that do not meet positive criteria.

BASED ON THE CRITERIA ABOVE we are clueless

----------------------

PAGE 1 of 2

Lyme Ab/Western Blot Reflex
Lyme Disease Ab, Quant, IgM 1.13 result high/ Flag
Note: IgM levels may peak at 3-6 weeks post infection, then gradually decline. FDA currently advises that Western Blot testing be performed following all equivocal or positive EIA results. Final diagnosis should include appropriate clinical findings and a psitive EIA which is also psitive by Western Blot.
Lyme Ab IgM Interp., EIA Positive Abnormal

---------------------

GP has referred hubby to an infectious disease specialist. I am concerned this doctor may not be lyme "friendly" - is this a step in the right direction or should I go looking for an LLMD right away now? Could this referral actually be an LLMD?

This Infec. Dis. specialist is in northern new jersey - if someone would like to PM me if they have compiled a list I would like to give you the doctor's name and see if the doctor is on the list. Thanks.

Post Edited (chicksinger) : 1/14/2011 5:27:12 PM (GMT-7)

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Traveler
Elite Member
Joined : May 2007
Posts : 36543
Posted 1/14/2011 7:19 PM (GMT -8)
HI Chicksinger,
I sure wish I could be of some help with interpreting those test results. Hopefully someone has seen results reported like this before can help you.

What you can do your self is to call that Infectious Disease Docs office and ask what their approach is to Lyme Disease. Please keep in mind that there are a whole lot of Infectious Disease docs that are not Lyme-literate.
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nasalady
Veteran Member
Joined : Sep 2009
Posts : 1176
Posted 1/14/2011 8:38 PM (GMT -8)
Hi Chicksinger,

Those results ARE confusing! I think I know what might be going on.....but someone please correct me if I'm wrong!

Lyme IgG/IgM Ab RESULT <0.91 paper criteria reads that NEGATIVE

Lyme Disease Ab, Quant, IgM RESULT: FLAGGED HIGH 1.13 - paper criteria POSITIVE >1.09 being POSITIVE

Lyme Ab, IgM, Interp., EIA Positive Abnormal


The result above is the EIA (enzyme immunoassay), which was positive for IgM, but negative for IgG.

The Western Blot results were negative by CDC criteria:

Lyme IgG WB Interp. - NEGATIVE

Lyme IgM WB Interp. NEGATIVE


Unfortunately the lab only reported that certain bands required by CDC criteria were absent; they did NOT report whether or not any of the OTHER bands showed up.

I hope this helps!
JoAnn
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nasalady
Veteran Member
Joined : Sep 2009
Posts : 1176
Posted 1/14/2011 8:42 PM (GMT -8)
P.S. Ask your infectious disease specialist if he/she belongs to the IDSA and/or ILADS. You want to have a doctor who belongs to ILADS, if at all possible! Those are the good guys! smilewinkgrin
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Razzle
Veteran Member
Joined : Aug 2007
Posts : 4415
Posted 1/15/2011 12:27 AM (GMT -8)
If I were you, I'd be looking for a Lyme-Literate MD right away instead of waiting.
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springsjean
Veteran Member
Joined : Mar 2009
Posts : 2185
Posted 1/15/2011 7:02 AM (GMT -8)
I went to infectious disease dr. in my plan and recommended by one of the lyme organizations. Wrong move. He was extremely nice and treated me but in the long run, he knew nothing about lyme. I got worse. Everything he told me turned out to be wrong. Told me you could only herx for a day at most, never heard of a CD-57, and ran tests for bizarre other ailments, claiming that it could not be lyme making me as sick as I was.

Please get to an LLMD. You will be wasting your time and your health. This doctor is a well known, well respected doctor but does not know lyme and in my opinion, not many doctors do.
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