IgM and IgG and ehrlichiosis

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Veteran Member

Date Joined May 2006
Total Posts : 1477
   Posted 2/8/2011 10:19 PM (GMT -7)   
Who knows about the difference in treatment for IgM and IgG.

also what is the difference between the Igenex test

HGE PANEL (granulocytic) my result is A. phatocytophilus IgM 1:20

IgG 1:40

suposedly it means positive or may indicate progression of the disease and /or treatment

(does that even make sense?)

Then the other page is

HME PANEL (monocytic)

E. chaffeensis IgM < 1:20

IgG < 1:40

this one is supposed to be negative

anyone know the treatment for this???

Veteran Member

Date Joined Aug 2007
Total Posts : 4399
   Posted 2/9/2011 1:15 AM (GMT -7)   
These tests show results for two different infections:  HGE (called Human Anaplasmosis now), and HME (Human monocytic ehrlichia).  They are similar organisms, and are considered the easiest of the coinfections to get rid of.
Treatment for both HGE and HME is Doxycycline, possibly a few others.  I also think the core Buhner protocol, and some of the other herbal protocols, can kill these two coinfections (Anaplasmosis, and HME).

On the progression, because you show both elevated IgM and IgG titers for the HGE, this means your body is currently in the process of converting the IgM to the IgG type of antibodies. Remember, according to the traditional infectious disease model, IgM antibodies are created during active infection, and then the body converts the IgM antibodies into IgG antibodies after a couple months. This may mean that your current treatment is helping, or that your immune system is kicking this infection, or that the infection is going "underground" (going into hiding - thus "progressing").

So I think the best thing to do is talk about these results with your current LLMD, and ask about treatment options (since I seem to remember that you had a lot of difficulty tolerating the doxycycline).

Good luck,

Chronic Lyme, Bart., Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut dysmotility & non-specific inflammation, UCTD, Osteoporosis, etc.; G-Tube
Meds: Cipro, Claritin, Domperidone, nutritional supplements, homeopathy, probiotics, etc.

Post Edited (Razzle) : 2/9/2011 1:18:14 AM (GMT-7)

Forum Moderator

Date Joined Mar 2009
Total Posts : 2154
   Posted 2/9/2011 2:19 PM (GMT -7)   
I tested positive for HME last year at 1:320 and after being on antibiotics for 18 months since then I was showing signs of the disease (sweating, headache) and now test positive at 1:512 (!) for HGE. I have read though that they can cross-react (?). Very strange. LLMD Dr. said treatment is doxy which I was on for about 3 months previously before infectious disease dr.took me off. She put me on doryx which is slow release doxy. However, after taking 2 a day for 2 weeks, just found out insurance company will not cover 2 a day so now I have none left and cannot renew for 2 more weeks! Ugh. I do have some doxy left though so I start taking that. Doryx is extremely expensive! Best of luck to you. Hope it is easy to get rid of - I'd be thrilled!
Lyme, HME, HGE, bartonella. 4 years undiagnosed despite 10 drs.
Current meds: roxythyroxine, bactrim, doryx, amanatadine, neurontin, xanax, valtrex, cymbalta
Prior meds: amoxicillin, probenecid, minocycline, tetracycline, doxy. IV refused by insurance. Supplements: potassium, boluke, alpha lipoic acid, ag immune, magnesium, milk thistle

Regular Member

Date Joined Oct 2010
Total Posts : 84
   Posted 2/9/2011 2:40 PM (GMT -7)   

IgM vs IgG

An immunoglobulin or antibody refers to proteins that bind to antigens in specific cases. Both IgM and IgG refer to a class of immunoglobulin. Antibodies are produced by the immune system to fight antigens like bacteria and viruses. IgM refers to those antibodies that are produced immediately after an exposure to the disease, while IgG refers to a later response. IgG generally confers immunity to a patient so far as that particular disease is concerned.

My infection is stuck in my IgM as I am not making antibodies, Dr C says that is a bad thing and that is why I am so ill.


Veteran Member

Date Joined May 2006
Total Posts : 1477
   Posted 2/9/2011 4:31 PM (GMT -7)   
Hey Suzi..I was hoping to hear from you on this. I looked up my results after you posted something about different treatment for Igm and IGG

please keep us posted. . do you know your numbers?

what is he giving you? for what?
20 yrs of doctors . DEC. 2009 tested positive for lyme, bartonella, ehrichiosis, HHPV6, chlamadyal pneumonia .
parasites :strongylides, diaoebia fragialis, hook worm.

Hep C ....fibro, rhumatoidal,depression,
New Topic Post Reply Printable Version
Forum Information
Currently it is Thursday, December 14, 2017 8:35 AM (GMT -7)
There are a total of 2,905,308 posts in 318,851 threads.
View Active Threads

Who's Online
This forum has 158208 registered members. Please welcome our newest member, Droid1.
362 Guest(s), 9 Registered Member(s) are currently online.  Details
Radi, HaleyBugs07, Dogdays, Eph, Lynnwood, cr3ativegirl, ks1905, dbell, iPoop